PAPERS

2022

Taranda J, Mathew G, Watrud K, El-Amine N, Lee MF, Elowsky C, Bludova A, Escobar Avelar S, Nowak DG, Wee TL, Wilkinson JE, Trotman LC, Osten P. Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases Cell Rep 2021, Nov 16;37(7):110027 PubMed

2019

Nowak DG, Katsenelson K, Watrud K, Chen M, Mathew G, D’Andrea V, Lee MF, Swamynathan M, Casanova-Salas I, Jibilian M, Buckholtz C, Ambrico A, Chun-Hao Pan, Wilkinson JE, Newton A, Trotman LC. The PHLPP2 phosphatase is a druggable driver of prostate cancer progression. J Cell Biol. 2019, Jun 03;(218)(6) PubMed

2017

Alexander J, Jude Kendall J, McIndoo J, Rodgers L, Aboukhalil R, Stepansky A, Sun G, Riggs M, Cox H, Hakker I, Nowak DG, Laze J, Llukani E, Srivastava A, Gruschow S, Singh S, Robinson B, Tewari A, Atwal G, Trotman LC, Lepor H, Hicks J, Wigler M, Krasnitz A.  Utility of Single-Cell Genomics in Diagnostic Evaluation of Prostate Cancer. Cancer Res. 2017, 78(2):348-358. PubMed

Chen M & Nowak DG, Navneet N, Robinson B, Watrud K, Ambrico A, Herzka TM, Zeeman ME, Minderer M, Zheng W, Ebbesen SH, Plafker KS, Stahlhud C, Wang VMY, Wills L, Nasar A, Castillo-Martin M, Cordon-Cardo C, Wilkinson JE, Powers S, Sordella R, Altorki NK, Mittal V, Stiles BM, Plafker SM, Trotman LC.The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol. 2017, 216(3):641-656. PubMed

Senturk S, Shirole NH, Nowak DG, Corbo V, Pal D, Vaughan A, Tuveson DA, Trotman LC, Kinney JB, Sordella R.  Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization. Nat Commun. 2017, 8:14370.PubMed

2015

Nowak DG, Cho H, Herzka T, Watrud K, DeMarco DV, M Y Wang V, Senturk S, Fellmann C, Ding D, Beinortas T et al..  2015.  MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discov. 2015, 5(6):636-51. PubMed